Bioinorganic Chemistry

Green Research Group, TCU

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Kayla N. Green

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The Green research group focuses on applications at the interface of chemistry and biology.  The areas of interest include coordination chemistry of relevance to:

(1) Treatment of Alzheimer’s disease with amine heterocyclic ligands.

(2) Responsive MRI sensors for oxidative stress. 

(3) Ferrocene-peptide conjugates as biosensors for cancer markers. 

These projects have aspects that are appropriate for both graduate and undergraduate students interested in the broad fields of bioinorganic and analytical chemistry and will serve as an excellent learning platform for students to develop the fundamental research skills and critical thinking needed to perform quality research.


Group News


02/10/13  Welcome New Group Members Hannah Johnston and Sean Rodich!

We have two recently accepted articles! 

Lincoln, K. M.; Offutt, M.; Hayden, T.; Saunders, R.; Green, K. N., “The Structural, Spectral and Electrochemical Properties of Ni(II), Cu(II) and Zn(II) Complexes Containing 12-membered Pyridol-based Tetra-aza Macrocycles", Inorg. Chem2014, 53, 1406-1416. DOI:10.1039/C2CC36808K

 Moore, A.; Shufelt, K.; Janesko, B. G.; Green, K. N. “Ligand effects on electrochemistry of bimetallic tungsten(0)/ ferrocene(II) systems”,  Accepted to Polyhedron. DOI: 10.1016/j.poly.2014.01.023

05/06/13  Congratulations to our group members for their recent awards as well as our graduating seniors.

Ryker Saunders ACS-DFW Student Award for TCU.                                                                                                                                                                  

Trang Nguyen:  TCU's ACS Undergraduate Award in Inorganic Chemistry.                                                                                         

Green Group Class of 2013:  Michael Offutt, Kimberly Hyde, Trang Nguyen, & Abby Moore.    

03/28/13 Welcome new graduate student Curtis Collier!

Congratulations Undergraduate researcher Kimberly Hyde who was named the Biology Department's Senior Scholar.

02/25/13  Our ChemComm paper is now published!  Congratulations Green Group Members. 

"A potent antioxidant small molecule aimed at targeting metal-based oxidative stress in neurodegenerative disorders" Kimberly Lincoln, Paulina Gonzalez, Timothy Richardson, David Julovich, Ryker Saunders, Jim Simpkins & Kayla Green. Chem. Comm. 2013, DOI: 10.1039/C2CC36808K. 

11/20/12  Hooray for Hunter!  He was selected to receive a “Commended Presentation” Award for his presentation at the  Rice University Undergraduate Symposium October 20, 2012. 

10/31/12  Check out our collaborative work (electrochemistry) with researchers at the UNT Health Science Center:  "Neuroprotective Actions of Methylene Blue and Its Derivatives" PLoS ONE 7(10): e48279. doi:10.1371/journal.pone.0048279

10/24/12  Kimberly Hyde and Hunter Scarborough were awarded SERC Grants for their respective projects in our group.  Thank you and congratulations to Kim and Hunter!! 

10/1/12  The Green research group welcomes new graduate student Samantha Dionicio!

08/31/12  Congratulations AD subgroup - The ACS Chemical Neuroscience paper has been accepted! 

11/28/11  Kayla's graduate advisor Marcetta Darensbourg was interviewed for "voices of inorganic chemistry" (Click here!)

10/6/11  Paulina passed her literature seminar!  “Catalysis at the Interface of Biology and Chemistry: Lewis Acid Asymmetric Catalysis Using Metalloenzymes ”

10/11  Congratulations to Kyle!  TCU Undergraduate Research and Creative Activity Initiative Grant  Recipient.

4/28/11  Kimberly was awarded “Outstanding  Teaching Assistant” by the Chemistry Faculty.  Congratulations! 

4/20/11 Kara was awarded the ACS-DFW Student Award for TCU.

4/16/11  Kimberly and Paulina both presented great talks at the 44th Annual DFW Meeting in Miniature.

Kimberly “Pyclen, A Potential Compound for Treatment of Alzheimer’s Disease”

Paulina “Trojan Horse Molecules for Metal ion Extraction from Beta-Amyloid:  Applications to Alzheimer’s Disease”

3/20/11 Kara presented her poster on Ferrocene biosensors at the National ACS meeting in Anaheim.

3/9/11 Congratulations!!  Kimberly passed her literature seminar!  “Insights into Rational Design of GluK1 Receptor Antagonists as Potential Anticonvulsant Analogs”

Kayla N. Green, Ph.D.

Department of Chemistry

Texas Christian University

Box 298860

Fort Worth, TX 76129