Publications (2019-Present)

Research from the Green Group at Texas Christian University

Click here to access Kayla's Full ORCID Profile

EUK-134 Activity
Fundamental Kinetic and Selective Properties of the Anti-Aging Antioxidant-Active Ingredient EUK-134

Authors: Nora Del Bosque, Grant T. Elam, David M. Freire, Timothy J. Hubin, and Kayla N. Green

Dalton Trans., 2026, 55, 2657-2664

IC_CC
Direct Arylation of Unactivated Arenes Using Earth Abundant Iron/Tetra-Aza Macrocyclic Complexes

Authors: Tahmina Afroz, David Freire, Timothy Hubin, Kayla N. Green

Inorg. Chem. 2026, 65, 5, 2812-2820. 

Effect of 4-position pyridine ring substitution on Zn(II) complexes
Effect of 4-position pyridine ring substitution on Zn(II) complexes of 4-substituted Py2N2 pyridinophane macrocycles

Authors: Katherine J. Smith, Timothy M. Schwartz, Hannah M. Johnston, David M. Freire, Kristof Pota, Kayla N. Green

Journal of Coordination Chemistry, 2025, 78:1-3, 225-232.

Predicting pKa of flexible polybasic tetra-aza macrocycles
Predicting pKa of flexible polybasic tetra-aza macrocycles

Authors: Tatum K. Harvey, Kristof Pota, Magy M. Mekhail, David M. Freire, Donatus A. Agbaglo, Benjamin G. Janesko, Kayla N. Green

RSC Adv., 2025, 15, 10663-10670.

Rings of Power: Controlling SOD Mimic Activity
Rings of Power: Controlling SOD Mimic Activity by the Addition of Pyridine Rings within the Pyridinophane Scaffold

Authors: Katherine J. Smith, Timothy M. Schwartz, David M. Freire, Cameron J. Bowers, Sarah K. Dunn, Jackson F. Bonnell, Magy A. Mekhail, Giridhar Akkaraju, Kayla N. Green

Inorg. Chem. 2024, 63, 50, 23544–23553.

Impact of Indole Inclusion in the Design of Multi-Tactical Metal-Binding Tetra-Aza Macrocycles
Impact of Indole Inclusion in the Design of Multi-Tactical Metal-Binding Tetra-Aza Macrocycles that Target the Molecular Features of Neurodegeneration

Authors: Kristof Pota, Shrikant Nilewar, Christina Mantsorov, Lindsay Zumwalt, Nam Nguyen, Cameron J. Bowers, David M. Freire, Robert B. Benafield III, Giridhar R. Akkaraju, Kayla N. Green

ACS Chem. Neurosci. 2024, 15, 20, 3776-3790.

Fe–L Coupling figure
Pyridine modifications regulate the electronics and reactivity of Fe-pyridinophane complexes

Authors: Magy A. Mekhail; Kristof Pota; Sugam Kharel; David M. Freire; Kayla N. Green

Dalton Trans., 2023, 52, 892-901.

JIBC figure
Synthesis and characterization of two piperazine containing macrocycles and their transition metal complexes

Authors: Kristof Pota; Hannah M. Johnston; Enikő Madarasi; Gyula Tircsó; Kayla N. Green

Journal of Biological Inorganic Chemistry 2023, 241, 112124.

Hydrogen Peroxide Disproportionation Activity
Hydrogen Peroxide Disproportionation Activity Is Sensitive to Pyridine Substitutions on Manganese Catalysts Derived from 12-Membered Tetra-Aza Macrocyclic Ligands

Authors: David M. Freire, Hannah M. Johnston, Katherine J. Smith, Kristof Pota, Magy A. Mekhail, Sugam Kharel, Kayla N. Green

Inorganic Chemistry. 2023, 62(39), 15842-15855.

JIBC figure
Increased Efficiency of a Functional SOD Mimic Achieved with Pyridine Modification on a Pyclen-Based Copper(II) Complex

Authors: Magy A. Mekhail; Katherine J. Smith; David M. Freire; Kristof Pota; Nam Nguyen; Marianne E. Burnett; Kayla N. Green

Inorg. Chem. 2023, 62, 14, 5415–5425.

EyeWork figure
A macrocyclic molecule with multiple antioxidative activities protects the lens from oxidative damage

Authors: Jinmin Zhang; Yu Yu; Magy A. Mekhail; Hongli Wu; Kayla N. Green

Frontiers in Chemistry 2022, 62, 14, 5415–5425.

EyeWork figure
A macrocyclic molecule with multiple antioxidative activities protects the lens from oxidative damage

Authors: Hannah M. Johnston; David M. Freire; Christina Mantsorov; Nena Jamison; Kayla N. Green

Eur. J. Inorg. Chem. 2022, e202200039.

Helix figure
pH-Dependent Concatenation of an Inorganic Complex Results in Solid State Helix Formation

Authors: Emily Hoffer, Brian P. Niebuhr, Kristof Pota, Timothy M. Schwartz, Marianne E. Burnett, Timothy J. Prior, Horst Puschmann, Kayla N. Green

Inorganica Chimica Acta, 2021, 120740

Mechanistic Insights into Iron Catalyzed C_H Bond Activation and C_C Coupling

Authors: Samantha M. Brewer, Timothy M. Schwartz, Magy A. Mekhail, Lara S. Turan, Timothy J. Prior, Timothy J. Hubin, Benjamin G. Janesko, Kayla N. Green

Organometallics, 2021, DOI: 10.1021/acs.organomet.1c00211

Electronic influence of substitution on the pyridine ring within NNN pincer-type molecules
Electronic influence of substitution on the pyridine ring within NNN pincer-type molecules

Authors: Schwartz, T. M.; Burnett, M. E.; Green, K. N.

Dalton Trans. 2020, 49, 2356-2363.

Functionalized Pyridine in Pyclen based Iron(III) Complexes: Evaluation of Fundamental Properties

Authors: Magy A. Mekhail, Kristof Pota, Timothy M. Schwartz, Kayla N. Green

RSC Advances, 2020, 10, 31165-31170

Hydrogen peroxide Disproportionation with Manganese Macrocyclic Complexes of Cyclen and Pyclen

Authors: David M. Freire, Debora Beeri, Kristof Pota, Hannah M. Johnston, Philip Palacios, Brad S. Pierce, Benjamin D. Sherman, Kayla N. Green

Inorg. Chem. Front., 2020, 7, 1573-1582

Manganese Complex of a Rigidified 15-Membered Macrocycle: A Comprehensive Study

Authors: Kristof Pota, Eniko Molnar, Ferenc Krisztian Kalman, David M. Freire, Gyula Tircso, Kayla N. Green

Inorg. Chem. 2020, 59, 16, 11366-11376

Helix figure
Dialing in on pharmacological features for a therapeutic antioxidant small molecule

Authors: Kayla N. Green, Kristof Pota, Gyula Tircso, Reka Anna Gogolak, Olivia Kinsinger, Collin Davda, Kimberly Blain, Samantha M. Brewer, Paulina Gonzalez, Hannah M. Johnston, Giridhar Akkaraju

Dalton Transactions, 2019, 48, 12430-12439

Synthesis of 12 Membered Tetra-aza Macrocyclic Pyridinophanes Bearing Electron-Withdrawing Groups

Authors: Akop Yepremyan, Magy A. Mekhail, Brian P. Niebuhr, Kristof Pota, Nishanth Sadagopan, Timothy M. Schwartz, Kayla N. Green

J. Org. Chem. 2020, 85, 7, 4988-4998

Environmental effects of chitosan as an immobilization medium
Environmental effects of chitosan as an immobilization medium for electrochemically active small molecules

Authors: Burnett, M. E.; Bodiford, N.; Coffer, J. L.; Green, K. N.

Journal of Coordination Chemistry, 2019, 72(13), 2160–2176

Enhancement of antioxidant activity and neurotherapeutic features through pyridol addition to tetra-azamacrocyclic molecules
Enhancement of antioxidant activity and neurotherapeutic features through pyridol addition to tetra-azamacrocyclic molecules

Authors: Johnston, H. M.; Pota, K.; Barnett, M. M.; Kinsinger, O.; Braden, P.; Schwartz, T. M.; Hoffer, E.; Sadagopan, N.; Nguyen, N.; Yu, Y.; Gonzalez, P.; Tircso, G.; Wu, H.; Akkaraju, G.; Chumley, M. J.; Green, K. N.

Inorganic Chemistry 2019, 58(24), 16771-16784.